Development of a Novel Plasma Fractionation Process for the Production of Immune Globulin


Type: Case Study

Problematic Host Cell Proteins – Clusterin

When doing Host Cell Protein analysis by mass spectrometry, we often fail to appreciate the “why” of the HCPs that show up in our protein lists – why did these HCPs co-purify with the Product, and why are they important?   Clusterin shows up in almost every HCP project we work on. Why?

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