Learn how Prolytix designed and implemented a custom ADA assay to help overcome a critical obstacle for a biopharma sponsor who was preparing for IND submission.
Overcoming Drug Interference in an IND-Track ADA Assay Read More »
Human blood plasma is rich in proteins, including immunoglobulins (IgG), coagulationfactors (Factors II, VIII, IX, and X), alpha-1 antitrypsin, fibrin sealants, and albumin.These proteins boost the immune system and fight inflammation and infection, makingplasma-derived biotherapeutics useful in treating rare, chronic, and often geneticdiseases. Unfortunately, the current worldwide demand for intravenous IgG (IVIG)products exceeds current plasma
Case Study: Improving IVIG Yield Without Cohn Fractionation Read More »
Learn more in our case study on how we used our advanced HRMS capabilities, detailed analytical outputs, and close, transparent communication to quickly identify high-risk proteins and advise process changes to de-risk a client’s biotherapeutic. Read the Case Study Now:
Case Study: De-Risking with HRMS HCP Analysis Read More »
A highly efficient method of plasma fractionation that has the potential to address the growing global IG product shortage. Read the Case Study Now:
Developing a New Plasma Fractionation Process for IVIG Read More »
When doing Host Cell Protein analysis by mass spectrometry, we often fail to appreciate the “why” of the HCPs that show up in our protein lists – why did these HCPs co-purify with the Product, and why are they important? Clusterin shows up in almost every HCP project we work on. Why?
HCP Watchlist: Clusterin and Its Impact on Biologics Read More »
