Post-Translational Modification

Post-Translational Modification Characterization

Peptide mapping provides information about the primary structure as well as the location and extent of post-translational modifications (PTMs) within a protein. Prolytix offers a complete portfolio of solutions for PTM characterization to help you understand the biological structure of proteins and their biological processes.

Customized PTM Characterization From Prolytix

We often use specialized conditions to fully characterize PTMs. A customized approach allows us to provide you with the most comprehensive information about a product. 

Whether we use different enzyme digests or different MS/MS conditions, Prolytix takes all factors into account when developing a PTM characterization approach.

Modifications include:

  • Deamidation
  • Oxidation
  • N-glycosylation
  • O-glycosylation
  • Disulfide mapping
  • Pegylation
  • Phosphorylation, acetylation, and more

PTM With High-Resolution Mass Spectrometry

High-resolution mass spectrometry (HRMS) allows us to perform the highest quality analysis. Our scientists have experience in multiple sensitive approaches and methods, which allows us to provide the data you need to move your project forward.