Protein identification and quantitation is an important early step in large molecule discovery. Prolytix uses label-free analysis methods to identify and quantify the proteins in your sample and their distinct characteristics. Speak with one of our scientists to learn more about our processes and our custom approach. Proteomic Analysis Applications
Sequence Variant Analysis Services for Therapeutic Proteins Don’t let sequence variants halt your viral vector or recombinant protein product development. Sequence variant analysis (SVA) is a challenging discipline that involves careful data analysis. Undetected sequence variants can affect a product’s safety and efficacy. Because sequence variants affect biological properties, early detection is key. Prolytix has …
Capsid Characterization Services for Vaccines and Viral Vectors For recombinant protein vaccines and viral vector development, including adeno-associated virus (AAV) development, viral capsid characterization with peptide mapping is an important step for ensuring drug product safety and consistency. Whether you’re developing a viral vector for a novel gene therapy or a preclinical vaccine, Prolytix has …
N-Glycan and Glycopeptide Analysis Services Have confidence in the consistency of your biotherapeutics manufacturing with glycosylation, including N-glycan analysis, from Prolytix. Our expertise includes tailored methods for neutral and highly sialylated glycans, mass spectrometry detection for glycan identity, and fluorescence detection for routine use. Glycosylation, a common post-translational modification (PTM), plays an important role in recombinant …
Post-Translational Modification Characterization Services Peptide mapping provides information about the primary structure as well as the location and extent of post-translational modifications (PTMs) within a protein. Prolytix offers a complete portfolio of solutions for PTM characterization to help you understand the biological structure of proteins and their biological processes. Customized PTM Characterization From Prolytix We …
Peptide Mapping Services With High-Resolution Mass Spectrometry (HRMS) Gain full understanding of your protein’s structure with Prolytix as your peptide mapping CRO. Using a multidisciplinary, bottom-up approach powered by high-resolution mass spectrometry (HRMS), our scientists determine protein identity and sequence coverage, as well as the location and extent of post-translational modifications (PTMs). This information is …
Confirm safety and efficacy of your biologic with host cell protein (HCP) analysis services from Prolytix. Prolytix uses high-resolution mass spectrometry (HRMS) to provide phase-appropriate methods for HCP analysis of biotherapeutics from early-phase development through GMP release testing. Using a consultative approach, we identify and mitigate HCPs to help ensure product purity and safety. We …
